Human Space Flight - NANOPARTICLES AND OSTEOPOROSIS

One of the in vitro scientific experiments of the Futura Mission 
of the italian Air Force captain, Samantha Cristoforetti .


The project's people 

PI, Livia Visai, Ph.D ( UNIPV, Pavia)

Co-PI, Angela Maria Rizzo, Ph.D ( UNIMI, Milano)

Co-PI, Giuseppina Rea, Ph.D (CNR-IC, Roma)

Industrial partner : Kayser Italy, Marco Vukich, Ph.D ( KI, Livorno) 




Project background



Microgravity (MG) significantly modifies the metabolism of bone tissue leading to site-specific alterations in the remodeling process causing an osteoporosis-like loss in bone mass and density. 
The project idea is focused on the development of a nanotechnology approach as a countermeasure to reduce MG-induced microgravity. RNA-Seq technique will be exploited to unravel gene expression remodeling in response to microgravity and nanoparticles exposure in order to identify new therapeutic targets for treating osteoporosis.











If you have any comments, please feel free to send a massage to the following E-mail address: nanospace@unipv.it.